生醫所106-1專題演講活動,敬邀 中央研究院生物化學研究所 凌嘉鴻助研究員授進行專題演講
演講主題為:
Genome engineering using CRISPR/Cas9
Abstract
The CRISPR/Cas9 system is a robust genome editing technology that works in human cells, animals, plants and microbes based on the RNA-programmed DNA cleaving activity of the Cas9 enzyme. This presentation provides a quick overview of the fascinating journey through which the studies of CRISPR microbial immune system rapidly revolutionizes the research in genome and cell biology. We will discuss the current development of the CRISPR/Cas9 technology, and the strength and weakness of this system. Through real case studies, we will understand the unsolved problems in CRISPR/Cas9-mediated genome engineering and discuss the challenges to overcome to realize its therapeutic potential.